My Chemical Romance has been described as punk, rock, pop punk, post-hardcore, art rock, and more. The band has also been described as emo, emo punk, and emo pop, but Gerard Way, lead singer of the band, has categorically denied the label of “emo,” saying in a 2007 interview with the Maine Campus:

Basically, it’s never been accurate to describe us. Emo bands were being booked while we were touring with Christian metal bands because no one would book us on tours. I think emo is F–ing garbage, it’s bulls–. I think there’s bands that unfortunately we get lumped in with that are considered emo and by default that starts to make us emo. All I can say is anyone actually listening to the records, put the records next to each other and listen to them and there’s actually no similarities. I think emo’s a pile of s–.

In the immediate wake of the 2001 September 11 attacks, singer Gerard Way started the band My Chemical Romance with the goal of "making a difference." The song “Skylines and Turnstyles” was written about the 9/11 attacks and is featured on the band’s first studio album I Brought You My Bullets, You Brought Me Your Love, released on July 23, 2002.

My Chemical Romance was formed by Gerard Way in Newark, New Jersey.

My Chemical Romance gets its name from Ecstasy: Three Tales of Chemical Romance, a book by Irvine Welsh. Mikey Way, the band’s bassist, suggested the name after seeing the book while working at a bookstore.

The original members of My Chemical Romance included:

• Gerard Way on lead vocals
• Mikey Way on bass
• Matt Pelissier on drums and percussion
• Ray Toro on lead guitar and backing vocals
• Frank Iero on rythym guitar and backing vocals

Pelsier left in 2004 and was replaced by Bob Bryar who remained the band’s drummer and percussionist until 2010 when he was replaced by Jarrod Alexander who remained with the band until it broke up in 2013. When the band reunited, Gerard and Mikey Way, Ray Toro, and Frank Iero returned with Jarrod Alexander as a touring member.

When the band embarked on The Black Parade World Tour in February 2007, Bob Bryar started experiencing wrist issues that caused him to be unable to perform with the band. Due to his injuries, he would officially depart from My Chemical Romance on March 3, 2010.

The Black Parade was released on October 20, 2006. It was the third studio album released by My Chemical Romance.

The My Chemical Romance fanbase is referred to as "Killjoys." The band's fourth studio album Danger Days: The True Lives of the Fabulous Killjoys is said to be the inspiration for the name.

On March 22, 2013, My Chemical Romance confirmed that it had broken up. Despite the band’s dissolution, My Chemical Romance released two albums before reuniting in 2017:

1. On March 25, 2014, the band released the greatest hits compilation album May Death Never Stop You
2. On September 23, 2016, the band released The Black Parade/Living with Ghosts, a 10 year anniversary re-release of The Black Parade.

My Chemical Romance officially announced its reunion on December 20, 2019. However, it was later revealed the band had actually reunited in 2017, more than 2 years prior to the official announcement.

My Chemical Romance has had 1,063 concerts.

My Chemical Romance is most often considered to be Rock, Punk, Alternative Rock, Hard Rock, Alternative, Punk Rock, Pop Punk, Emo, Post-Hardcore, Modern Rock, Pov: Indie, Rock Opera, and Emo Pop.

The next My Chemical Romance concert is on July 11, 2025 at T-Mobile Park in Seattle, Washington, United States. The bands performing are: My Chemical Romance / Violent Femmes.

The last My Chemical Romance concert was on October 20, 2024 at Las Vegas Festival Grounds in Las Vegas, Nevada, United States. The bands that performed were: My Chemical Romance / Fall Out Boy / A Day To Remember / Jimmy Eat World / Dashboard Confessional / Pierce the Veil / Simple Plan / The Used / Coheed and Cambria / Underoath / New Found Glory / The Distillers / Dance Gavin Dance / Mayday Parade / Motion City Soundtrack / Chiodos / Silverstein / Movements / Basement / Bayside / Sleeping With Sirens / The Maine / Neck Deep / Saves The Day / Cobra Starship / The Wonder Years / Story of the Year / The Starting Line / Say Anything / August Burns Red / Four Year Strong / Thursday / Mom Jeans. / State Champs / Senses Fail / Atreyu / 3OH!3 / Hawthorne Heights / Anberlin / Cartel / Armor for Sleep / Tonight Alive / Hey Monday / Saosin / The Devil Wears Prada / We The Kings / Escape the Fate / Pretty Girls Make Graves / Nada Surf / The Red Jumpsuit Apparatus / Emery / Alesana / Against the Current / L.S. Dunes / Millionaires / Daisy Grenade / The Forecast / We Are the In Crowd / CARR / Taking Back Sunday / Boys Like Girls / The Paradox / Travie McCoy / Patrick Stump / Kellin Quinn / Jason Aalon Butler / Jenna McDougall / Lenay / Travis Clark / Tay Jardine / tara yummy / Kayleigh Goldsworthy.

The songs that My Chemical Romance performs live vary, but here's the latest setlist that we have from the October 20, 2024 concert at Las Vegas Festival Grounds in Las Vegas, Nevada, United States:

1. The End.
2. Dead!
3. This Is How I Disappear
4. The Sharpest Lives
5. Welcome to the Black Parade
6. I Don't Love You
7. House of Wolves
8. Cancer
9. Mama
10. Sleep
11. Teenagers
12. Disenchanted
13. Famous Last Words
14. Blood
15. Na Na Na (Na Na Na Na Na Na Na Na Na)
16. Helena